Personalized ViscoElastic Testing-guided Bleeding Management In Liver Surgery, Neurosurgery and Obstetrics

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorMedical University of Vienna

About this trial

The ClotPro analyzer is a new generation viscoelastic analyzer for the in vitro assessment of blood coagulation. This study aims to assess the agreement of ClotPro 6.0, ROTEM delta, and TEG 6s in three distinct cohorts: i) patients with liver disease undergoing liver surgery, ii) pregnant women undergoing elective cesarean section, and iii) patients undergoing elective intracranial neurosurgery. Further coagulation tests will be performed (standard laboratory coagulation tests, thrombin and plasmin generation tests) in an exploratory fashion to compare them with viscoelastic test results. The obtained test results will not result in any diagnostic or therapeutic consequences for patients included in this study.

Eligibility criteria

Qualifiers

Vulnerable patient cohorts

Liver resection (anatomic or non-anatomic segmental resection, right or left hepatectomy, right or left extended hepatectomy),

Orthotopic liver transplantation,

Pregnant women undergoing an elective caesarean section, and

Disqualifiers

None

Trial design

Treatments tested in this trial

  • Viscoelastic testing

Treatment groups

240 Participants
are divided into 3 treatment groups

Sponsors and collaborators

Medical University of Vienna

Lead sponsor

Synapse - Research Institute Maastricht

Collaborator