Pharmaco-proteomic Platform to Evaluate Drug Interactions in Liver Transplant Patients

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorPontificia Universidad Catolica de Chile

About this trial

The goal of this observational study is to enhance the ability to forecast kidney failure in liver transplant patients in the ICU under multidrug treatment by developing a computer platform that integrates mathematical models of drug interactions, proteomics, and clinical data. The main outcomes it aims to develop are:

1. Design the multidrug web computing platform with available information on drug pair interactions (DDIs). 2. Integrate the proteomic and clinical data of liver transplant patients into the IT platform. 3. Implement the multidrug web platform to predict the clinical evolution of liver transplant patients.

Eligibility criteria

Qualifiers

Liver transplant patients undergoing surgery at UC Christus Hospital

Disqualifiers

Patients on renal replacement therapy

Patients for whom no clinical or pharmacological registry is available

Trial design

Treatments tested in this trial

  • Multi-drug interaction

Treatment groups

No treatment groups listed

Sponsors and collaborators

Pontificia Universidad Catolica de Chile

Lead sponsor

Universidad de Valparaiso

Collaborator

Universidad Adolfo Ibañez

Collaborator