About this trial
The goal of this observational study is to enhance the ability to forecast kidney failure in liver transplant patients in the ICU under multidrug treatment by developing a computer platform that integrates mathematical models of drug interactions, proteomics, and clinical data. The main outcomes it aims to develop are:
1. Design the multidrug web computing platform with available information on drug pair interactions (DDIs). 2. Integrate the proteomic and clinical data of liver transplant patients into the IT platform. 3. Implement the multidrug web platform to predict the clinical evolution of liver transplant patients.
Eligibility criteria
Qualifiers
Liver transplant patients undergoing surgery at UC Christus Hospital
Disqualifiers
Patients on renal replacement therapy
Patients for whom no clinical or pharmacological registry is available
Trial design
Treatments tested in this trial
- Multi-drug interaction
Treatment groups
Sponsors and collaborators
Pontificia Universidad Catolica de Chile
Lead sponsor
Universidad de Valparaiso
Collaborator
Universidad Adolfo Ibañez
Collaborator