Pharmacological Reversal of Neuromuscular Blockade in Critically Ill Patients
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age19-90
SponsorSeoul National University Hospital
About this trial
The goal of this clinical trial is to compare the effect of use of reversal agents for neuromuscular blockade in critically ill patients on time for neurological assessment after endotracheal intubation
The main questions it aims to answer are:
* The use of reversal agents for neuromuscular blockade after endotracheal intubation may reduce the time for neurological assessment. * The types of reversal agents for neuromuscular blockade may affect the time for neurological assessment.
Participants will receive different reversal agents or no medications based on the assigned groups. Thirty minutes after intubation using rocuronium, medication is administered, and the time of initial confirmation of eye opening and movement is recorded.
Researchers will compare 3 groups (sugammadex, neostigmine and control(no medication) to see the difference of time for neurological assessment after endotracheal intubation.
Eligibility criteria
Qualifiers
Adult patients 19 years of age or older who were intubated after admission to the intensive care unit.
Disqualifiers
Patients younger than 19 years of age
Patients who are not neurologically evaluable or have concomitant neurologic dysfunction
Patients with neuromuscular disorder
Patients with a history of drug allergic reactions to sugammadex or neostigmine
Trial design
Treatments tested in this trial
- Sugammadex
- Neostigmine
Treatment groups
30 Participants
are divided into 3 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov