9MW2821 Combined With Other Antitumor Drugs in Patients With Advanced Gynecological Tumors

Trial statusNot yet recruiting
Trial phasePhase 1, Phase 2
Trial typeInterventional
Biological sexFemale
Age18-75
SponsorMabwell (Shanghai) Bioscience Co., Ltd.

About this trial

To evaluate the safety, tolerability, and preliminary efficacy of 9MW2821 in combination with other anti-tumor agents in patients with advanced gynecological malignancies.

Eligibility criteria

Qualifiers

Competent to comprehend, sign, and date an independent ethics committee/institutional review board/research ethics board (IEC/IRB/REB) approved informed consent form.

Female subjects aged 18 to 75 years (including 18 and 75 years).

Eastern Cooperative Oncology Group (ECOG) performance status of 0 or 1.

Histopathological diagnosed of advanced gynecological tumors.

Disqualifiers

History of another malignancy within 3 years before the first dose of study drug.

Patients with ongoing clinically significant toxicities related to prior treatment.

Presence of Grade ≥ 2 peripheral neuropathy.

Exclusion of prior diseases and prior treatments as specified in the protocol.

Trial design

Treatments tested in this trial

  • 9MW2821+other anticancer therapy

Treatment groups

260 Participants
are divided into 1 treatment group