A Clinical Study of SHR-4685 on Safety, Tolerability and Pharmacokinetics in Participants With Solid Tumors

ConditionSolid Tumor
Trial statusNot yet recruiting
Trial phasePhase 1
Trial typeInterventional
Biological sexAll
Age18-75
SponsorSuzhou Suncadia Biopharmaceuticals Co., Ltd.

About this trial

The study is being conducted to evaluate the safety, tolerability and pharmacokinetics of SHR-4685 in participants with advanced solid tumors.

Eligibility criteria

Qualifiers

Have fully understood this study and voluntarily signed the informed consent form, with good compliance and cooperation with follow-up;

Age 18-75 years, any gender;

Performance status ECOG score 0 or 1;

Expected survival time greater than 3 months;

Disqualifiers

Participants who have received any approved anti-tumor drugs (including investigational anti-tumor drugs) within 4 weeks prior to the first dose of the IP;

Toxicities from prior anti-tumor therapy have not recovered to ≤ Grade 1 or to the level specified in the inclusion/exclusion criteria;

Presence of central nervous system (CNS) metastases;

Concurrent active malignancy other than the primary tumor;

Trial design

Treatments tested in this trial

  • SHR-4685

Treatment groups

170 Participants
are divided into 1 treatment group