A Clinical Study of T3011 in Combination With PD-1/PD-L1 Inhibitors in Subjects With Advanced Solid Tumors

Trial statusRecruiting
Trial phasePhase 1, Phase 2
Trial typeInterventional
Biological sexAll
Age18+
SponsorShanghai Pharmaceuticals Holding Co., Ltd

About this trial

This clinical study evaluated the efficacy and safety of T3011 in combination with PD-1/PD-L1 inhibitors in subjects with advanced solid tumors

Eligibility criteria

Qualifiers

Subjects with advanced solid tumors;

At least one measurable lesion;

Eastern Cooperative Oncology Group (ECOG) performance status 0 or 1;

Expected survival > 12 weeks;

Disqualifiers

Subjects who have received other antitumor therapy within the prescribed time prior to the first dose;

Subjects with a history of other malignancies within the prescribed time prior to the start of study treatment.

At screening, subjects with a history or evidence of high risk cardiovascular disease;

Subjects with persistent or active infection requiring intravenous anti-infective therapy;

Trial design

Treatments tested in this trial

  • T3011 high dose
  • T3011 middle dose
  • T3011 low dose

Treatment groups

68 Participants
are divided into 1 treatment group