About this trial
The purpose of the study is to evaluate the safety、tolerability and preliminary efficacy of B019 in subjects with relapsed or refractory B-cell non-Hodgkin's lymphoma.
Eligibility criteria
Qualifiers
Subjects who can fully understand this trial and voluntarily sign the informed consent form (ICF) before any research-related procedures;
Histologically confirmed B-cell non-Hodgkin's lymphoma (B-NHL) with specified pathological subtypes;
Histologically confirmed CD19 and/or CD22 positivity;
Expected survival time exceeding 12 weeks;
Disqualifiers
Primary central nervous system (CNS) lymphoma; However, secondary CNS lymphoma without clinical symptoms can be enrolled after being determined by the researchers;
Use of the prescribed drugs or treatments within the specified time before the collection of PBMC;
Prior allogeneic hematopoietic stem cell transplantation;
Systemic intravenous infusion treatment or uncontrollable bacterial, fungal or viral infection within 2 weeks before signing the ICF;
Trial design
Treatments tested in this trial
- B019