A Clinical Trial of TQB3909 Tablets in Combination With Azacitidine for the Treatment of Myeloid Malignancies

Trial statusRecruiting
Trial phasePhase 1, Phase 2
Trial typeInterventional
Biological sexAll
Age18+
SponsorChia Tai Tianqing Pharmaceutical Group Co., Ltd.

About this trial

This is an open, multi-center clinical study designed to evaluate the safety, tolerability and efficacy of TQB3909 tablets in combination with azacitidine in subjects with myeloid malignancies.

Eligibility criteria

Qualifiers

Voluntary and signed informed consent, good compliance

Age: ≥18 years old (at the time of signing the informed consent); expected survival time greater than 3 months.

Myelodysplastic Syndromes (MDS)

Major organ functions are normal.

Disqualifiers

Diagnosis of or current concomitant malignancy within 3 years prior to the first dose;

Presence of multiple factors affecting oral drug intake and/or absorption;

Major surgical procedures or significant traumatic injuries within 28 days prior to the first dose;

History of arterial/venous thrombotic events within 6 months prior to the first dose;

Trial design

Treatments tested in this trial

  • TQB3909 Tablets + Azacitidine

Treatment groups

138 Participants
are divided into 1 treatment group