A Randomized Controlled Trial of Oral CBD for the Treatment of Upper Extremity Musculoskeletal Pain
Trial statusNot yet recruiting
Trial phasePhase 1
Trial typeInterventional
Biological sexAll
Age18+
SponsorBrent DeGeorge
About this trial
The goal of this clinical trial is to learn about the use of cannabidiol (CBD) capsules as a treatment for musculoskeletal pain. CBD is commonly being used as an over-the-counter treatment for musculoskeletal pain. Clinical trials have demonstrated a pain-relief benefit for hand and wrist osteoarthritis with topical CBD, however patients prefer oral CBD and no clinical trial has been performed to establish efficacy of oral CBD in humans for upper extremity musculoskeletal pain. The main questions it aims to answer are:
Is CBD more effective than placebo at relieving pain for upper extremity musculoskeletal pain ? Is CBD safe for participants with upper extremity musculoskeletal pain?
Participants will:
take 4 weeks of daily CBD capsules take 4 weeks of daily placebo capsules answer surveys about how they are feeling and functioning.
Participants will \[describe the main tasks participants will be asked to do, interventions they'll be given and use bullets if it is more than 2 items\].
Eligibility criteria
Qualifiers
Provision of signed and dated informed consent form.
Stated willingness to comply with all study procedures and availability for the duration of the study.
Male or female, aged 18 years or older.
Daily visual analog pain score >5/10 and <9/10.
Disqualifiers
Subject does not speak or read English fluently.
Subject is blind.
Severe cardiac, pulmonary, liver and /or renal disease, or any other major organ dysfunction.
Subject with a history of symptoms (e.g., dizziness, light-headedness, blurred vision, palpitations, weakness, syncope) related to a drop in blood pressure due to postural changes.
Trial design
Treatments tested in this trial
- Cannabidiol (CBD)
- Placebo
Treatment groups
100 Participants
are divided into 2 treatment groupsSponsors and collaborators
Brent DeGeorge
Lead sponsor
University of Virginia
Sponsor institution
The Plastic Surgery Foundation
Collaborator
Source ClinicalTrials.gov