A Real-World Study of Fecal Transplants for Cancer Therapy Side Effects

Trial statusRecruiting
Trial phasePhase 1
Trial typeInterventional
Biological sexAll
Age18+
SponsorSecond Affiliated Hospital, School of Medicine, Zhejiang University

About this trial

The goal of this clinical trial is to learn if fecal microbiota transplantation can treat in Gastrointestinal cancer patients with chemotherapy / targeted gastrointestinal symptoms. The main question it aims to answer is: To evaluate the effect of fecal microbiota transplantation (FMT) on gastrointestinal tract in patients with gastrointestinal tumors.

Eligibility criteria

Qualifiers

Age ≥ 18 years, gender not restricted;

Estimated survival time ≥ 3 months;

Confirmed diagnosis of gastrointestinal tumors by pathological examination, including esophageal cancer, gastric cancer, colon cancer, rectal cancer, etc.;

TNM staging of cancer in patients is Stage IV;

Disqualifiers

Patients with major organ dysfunction or even failure, including but not limited to cardiac insufficiency or heart failure, renal insufficiency or renal failure, and hepatic insufficiency/hepatic failure;

Uncontrolled or severe infections;

Known history of psychotropic substance abuse, alcoholism, and drug abuse;

Patients with severe infections complicated with septicemia or sepsis;

Trial design

Treatments tested in this trial

  • Fecal microbiota transplantation (FMT)

Treatment groups

90 Participants
are divided into 2 treatment groups