About this trial
This is a single-center, single-arm, open investigator-initiated clinical study to evaluate the efficacy and safety of VRT106 in combination with chemotherapy in the treatment of resectable pancreatic cancer.
Eligibility criteria
Qualifiers
Subject voluntarily agrees to participate in this study and signs an Institutional Review Board -approved informed consent prior to performing any of the Screening Visit procedures.
Males and females at 18-75 years of age, inclusive, at the Screening Visit.
Have a clinical diagnosis of pancreatic cancer.
An Eastern Cooperative Oncology Group (ECOG) score of 0 or 1.
Disqualifiers
Prior treatment with other oncolytic virus or systemic therapy for pancreatic cancer.
Previous allogeneic hematopoietic stem cell transplantation or organ transplantation.
Immunocompromised patients.
Known alcohol or drug dependency.
Trial design
Treatments tested in this trial
- Oncolytic virus VRT106
- Chemotherapy
Treatment groups
Sponsors and collaborators
Guangdong Provincial People's Hospital
Lead sponsor
Guangzhou Virotech Pharmaceutical Co., Ltd.
Collaborator