A Study of CRD3874-SI in People With Leukemia

Trial statusRecruiting
Trial phasePhase 1
Trial typeInterventional
Biological sexAll
Age18+
SponsorMemorial Sloan Kettering Cancer Center

About this trial

The purpose of this study is to find out whether CRD3874-SI is a safe treatment for participants with acute myeloid leukemia (AML).

Eligibility criteria

Qualifiers

Documentation of Disease

Participant must be ≥ 18 years of age at the time of signing the informed consent form (ICF).

Participant must weigh at least 40 kg

Participant has an Eastern Cooperative Oncology Group (ECOG) performance status score 0-2 (See Appendix I for performance status criteria)

Disqualifiers

Participants with acute promyelocytic leukemia

Participants with isolated myeloid sarcoma

Blast phase of chronic myeloid leukemia

Known active central nervous system leukemia

Trial design

Treatments tested in this trial

  • CRD3874-SI

Treatment groups

24 Participants
are divided into 3 treatment groups