A Study of DeepTag-GPRC5D Targeted CAR-T Cells Therapy for Refractory/Relapsed Multiple Myeloma

Trial statusRecruiting
Trial phasePhase 1
Trial typeInterventional
Biological sexAll
Age18-75
SponsorHe Huang

About this trial

Clinical Trial for the safety and efficacy of DeepTag-GPRC5D targeted CAR-T cells therapy for refractory/relapsed multiple myeloma

Eligibility criteria

Qualifiers

1. Those who voluntarily participated in this trial and provided informed consent;

2. Gender unlimited,18<Age≤75;

3. Estimated life expectancy of minimum of 12 weeks;

4. ECOG 0-2;

Disqualifiers

1. History of craniocerebral trauma, conscious disturbance, epilepsy, cerebrovascular ischemia, and cerebrovascular hemorrhagic diseases;

2. Electrocardiogram shows prolonged QT interval, severe heart diseases such as severe arrhythmia in the past;

3. Pregnant (or lactating) women;

4. Patients with HIV infection;

Trial design

Treatments tested in this trial

  • DeepTag-GPRC5D Targeted CAR T-cells

Treatment groups

40 Participants
are divided into 1 treatment group

Sponsors and collaborators

He Huang

Lead sponsor

Zhejiang University

Sponsor institution

Yake Biotechnology Ltd.

Collaborator