A Study of Exercise and Pharmacologic Intervention on Systemic Inflammation
Trial statusRecruiting
Trial phasePhase 1
Trial typeInterventional
Biological sexAll
Age65-80
SponsorIcahn School of Medicine at Mount Sinai
About this trial
This is a study assessing the feasibility of performing an anti-aging intervention which is a combination of an exercise regimen, spermidine supplementation, and either rapamycin or lamivudine.
Eligibility criteria
Qualifiers
Patients 65-80 years old
Current or former smokers
BMI 25-32
No cancer requiring active therapy within the last 2 years
Disqualifiers
Patients may not have cancer requiring active therapy within the last 2 years
Patients may not have autoimmune disease requiring disease modifying agents
Patients may not be receiving immune modifying biologic therapies
Patients may not have chronic kidney disease stage 3/4 or end stage renal disease
Trial design
Treatments tested in this trial
- lamivudine
- rapamycin
- Exercise Regimen
- Spermidine
Treatment groups
22 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov