A Study of GNC-038 Injection in Patients With Relapsed or Refractory Non-Hodgkin's Lymphoma

Trial statusRecruiting
Trial phasePhase 1, Phase 2
Trial typeInterventional
Biological sexAll
Age18-75
SponsorSichuan Baili Pharmaceutical Co., Ltd.

About this trial

To explore the safety and preliminary efficacy of GNC-038 in patients with relapsed or refractory NHL, and to determine the MTD and RP2D of GNC-038, or the MAD and DLT

Eligibility criteria

Qualifiers

The subject is capable of understanding the informed consent form, voluntarily participates, and signs the informed consent form;

No gender restrictions;

Age: ≥18 years and ≤75 years;

Expected survival time ≥3 months;

Disqualifiers

Pulmonary diseases classified as ≥Grade 3 according to NCI-CTCAE v5.0; patients currently diagnosed with interstitial lung disease (ILD);

Active infections requiring systemic treatment, such as severe pneumonia, bacteremia, sepsis, etc.;

Active tuberculosis;

Patients with active autoimmune diseases;

Trial design

Treatments tested in this trial

  • GNC-038

Treatment groups

40 Participants
are divided into 1 treatment group

Sponsors and collaborators

Sichuan Baili Pharmaceutical Co., Ltd.

Lead sponsor

SystImmune Inc.

Collaborator

Baili-Bio (Chengdu) Pharmaceutical Co., Ltd.

Collaborator