A Study to Evaluate BMS-986470 in Healthy Volunteers and Participants With Sickle Cell Disease

Trial statusRecruiting
Trial phasePhase 1, Phase 2
Trial typeInterventional
Biological sexAll
Age18+
SponsorBristol-Myers Squibb

About this trial

The purpose of this study is to evaluate the safety and tolerability, pharmacokinetics and pharmacodynamics, pH and food effect, and preliminary efficacy of BMS-986470 in healthy volunteers and participants with sickle cell disease.

Eligibility criteria

Qualifiers

None

Disqualifiers

Cohort A and B.

Other protocol-defined Inclusion/Exclusion criteria apply.

Trial design

Treatments tested in this trial

  • BMS-986470
  • Placebo
  • Famotidine

Treatment groups

184 Participants
are divided into 5 treatment groups

Sponsors and collaborators