A Study to Evaluate the Efficacy and Safety of QLF31907 Combination Therapy in Patients With Advanced Malignant Tumors

Trial statusNot yet recruiting
Trial phasePhase 1, Phase 2
Trial typeInterventional
Biological sexAll
Age18+
SponsorQilu Pharmaceutical Co., Ltd.

About this trial

This study is designed to evaluate the safety and efficacy of QLF31907 combination therapy in advanced malignant tumors.

Eligibility criteria

Qualifiers

subjects voluntarily participated and signed a written informed consent form;

age ≥18 years, male or female;

ECOG PS 0-1;

histopathologically diagnosed advanced malignant tumors;

Disqualifiers

previous treatment with 4-1BB agonist or 4-1BB recombinant fusion protein;

received anti-tumor therapy within 4 weeks prior to the first study treatment;

history of autoimmune disease;

history of other active malignancies within 3 years prior to the first treatment;

Trial design

Treatments tested in this trial

  • QLF31907
  • Irinotecan
  • Docetaxel

Treatment groups

60 Participants
are divided into 2 treatment groups

Locations

This trial has no locations

Sponsors and collaborators