About this trial
An Study of Orally Administered RNK08954 in Healthy Adult Subjects to Determine the Effect of Food on the Pharmacokinetics of RNK08954,Mass Balance Study of \[14C\] RNK08954 in Chinese Healthy Adult Male Subjects
Eligibility criteria
Qualifiers
Healthy, adult, male or female, 18-45 years of age, inclusive, at the screening visit.
Male participants must have a body weight of no less than 50 kg, and female participants must have a body weight of no less than 45 kg. The Body mass index (BMI) should be between 19 and 26 kg/m² (inclusive).
Must follow protocol specified contraception guidance.
Understands the study procedures in the informed consent form (ICF), and be willing and able to comply with the protocol.
Disqualifiers
Clinically significant abnormalities found in comprehensive physical examinations, vital signs, laboratory tests, 12-lead electrocardiogram, chest X-ray, etc.
Positive results for hepatitis B surface antigen (HBsAg), hepatitis C virus antibody (HCV-Ab), human immunodeficiency virus antibody (HIV-Ab), or treponema pallidum antibody.
Individuals with allergic constitution.
Any history of clinically significant diseases or conditions that, in the investigator's judgment, may affect the trial results.
Trial design
Treatments tested in this trial
- RNK08954