A Trial of SHR-7787 Injection in Patients With Advanced Solid Tumors

Trial statusRecruiting
Trial phasePhase 1, Phase 2
Trial typeInterventional
Biological sexAll
Age18-75
SponsorShanghai Hengrui Pharmaceutical Co., Ltd.

About this trial

The study is being conducted to evaluate safety, tolerability, pharmacokinetics and preliminary efficacy of SHR-7787 injection monotherapy for patients with advanced solid tumors. To explore the reasonable dosage of SHR-7787 injection monotherapy for patients with advanced solid tumors.

Eligibility criteria

Qualifiers

Ability to understand and voluntarily agrees to participate by giving written informed consent for the study;

Patients with unresectable recurrent or metastatic solid tumors;

There is at least one lesion could be measured;

An Eastern Cooperative Oncology Group (ECOG) performance status (PS) score of 0 or 1;

Disqualifiers

Patients with known active central nervous system (CNS) metastases;

Subjects who had other malignancy in five years before the first dose;

Patients with tumor-related pain that cannot be controlled as determined;

Patients with serious cardiovascular and cerebrovascular diseases;

Trial design

Treatments tested in this trial

  • SHR-7787 injection

Treatment groups

201 Participants
are divided into 1 treatment group