About this trial
The study is being conducted to evaluate the safety, tolerability and efficacy of SHR-A2102 for injection with or without Antitumor Therapy in Advanced Solid Tumors. To explore the reasonable dosage of SHR-A2102 for Advanced Solid Tumors.
Eligibility criteria
Qualifiers
Have the ability to give informed consent, have signed informed and able to comply with the treatment plan to visit the tests and other procedural requirements;
The age of signing the informed consent is above 18 years old, regardless of gender;
The ECOG score is 0 or 1;
Expected survival ≥12 weeks
Disqualifiers
Inadequately treated central nervous system metastases or the presence of uncontrolled or symptomatic active central nervous system metastases;
Have previously received antiboy-coupled drugs containing topoisomerase I inhibitors; Stage II was previously treated with PD-1/PD-L1 inhibitors;
Systemic antitumor therapy was received 4 weeks before the start of the study;
Palliative radiotherapy was completed within 14 days before the first dose; Chest radiotherapy >30 Gy within 6 months prior to initial administration;
Trial design
Treatments tested in this trial
- SHR-A2102
- SHR-A2102 ; Adebrelimab injection