Anorectal Manometery in Pediatric Chronic Refractory Constipation
ConditionChronic Constipation
Trial statusRecruiting
Trial phasePhase 1, Phase 2
Trial typeInterventional
Biological sexAll
Age4-16
SponsorAin Shams University
About this trial
Anorectal manometry and high-resolution anorectal manometry (HRAM) are becoming the investigation of choice for understanding the pathophysiology of chronic constipation with or without fecal incontenance in children in many institutions. In high resolution anorectal manometery we are able to gain information whether the symptoms are related to sphincter dysfunction, impaired sensation, or pelvic floor dyssynergia
Eligibility criteria
Qualifiers
Children and adolescents aged from 4 to 16 years.
Participants fulfilling Rome IV criteria for the diagnosis of functional constipation.
2 or fewer defecations in the toilet per week
At least 1 episode of fecal incontinence per week
Disqualifiers
participants who have anorectal malformation
participants who have neurological disease affecting lower limbs
Has a history of hypersensitivity or allergies to lubiprostone
Trial design
Treatments tested in this trial
- lubiprostone , single arm
- biofeed back sessions
- botox injection
Treatment groups
60 Participants
are divided into 1 treatment groupSponsors and collaborators
Source ClinicalTrials.gov