Clinical and Radiographic Evaluation of Allogenic Dentin Grafts for Alveolar Ridge Preservation

Trial statusRecruiting
Trial phasePhase 1, Phase 2
Trial typeInterventional
Biological sexAll
Age18-60
SponsorJordan University Hospital

About this trial

For the first time, allografts from human-extracted teeth will be prepared and evaluated in a prospective clinical trial to assess their efficacy for alveolar ridge preservation. The reconstruction and preservation of the alveolar ridge after tooth extraction are essential for future prosthetic rehabilitation.

Autogenous bone grafts, while effective, are limited by donor site morbidity and insufficient graft quantity. Allogenic dentin grafts from healthy human donors present a scalable solution. This study aims to evaluate the biocompatibility and effectiveness of two types of allogenic dentin grafts-demineralized dentin allografts (DDA) and whole tooth allografts (WTA)-for alveolar ridge preservation, contributing to innovative, sustainable dental practices.

Eligibility criteria

Qualifiers

None

Disqualifiers

Students, interns, or residents willing to participate and provide informed consent.

No history of systemic diseases such as diabetes, hepatitis, or immune disorders.

Negative blood screening for HIV, HBV, and HCV.

Non-smokers or individuals who have not smoked within the last six months.

Trial design

Treatments tested in this trial

  • DDA
  • WTA

Treatment groups

10 Participants
are divided into 3 treatment groups

Sponsors and collaborators