Clinical Study of Curcumin in Preventing Postoperative Adhesion of Bilateral Vocal Cords

Trial statusRecruiting
Trial phasePhase 1, Phase 2
Trial typeInterventional
Biological sexAll
Age18-75
SponsorEye & ENT Hospital of Fudan University

About this trial

To provide a novel therapy idea and method to solve the clinical problem of postoperative adhesion of bilateral vocal cords, patients enrolled in this study will be applied with curcumin on both wound sites of bilateral vocal cords after the surgery on the bilateral vocal cord endoscopically.

Eligibility criteria

Qualifiers

Patients with bilateral vocal cord diseases who are going to undergo resection of bilateral vocal cord lesions endoscopically.

Patients with bilateral vocal cord adhesion who are going to undergo incision of bilateral vocal cord adhesion endoscopically.

Disqualifiers

Patients with other laryngeal diseases.

Patients with cardiac and pulmonary insufficiency.

Patients unable to cooperate with the follow-up on time after surgery.

Patients who refuse to sign the informed consent after notification.

Trial design

Treatments tested in this trial

  • Curcumin
  • Mitomycin-C

Treatment groups

100 Participants
are divided into 2 treatment groups