Comparison Of Clinical Outcomes of Intraperitoneal Bupivacaine Instillation Versus Placebo as Preemptive Analgesia in Patients Undergoing Open Appendectomy

ConditionAppendectomy
Trial statusRecruiting
Trial phasePhase 1
Trial typeInterventional
Biological sexAll
Age20-60
SponsorSardar Umer Rehman

About this trial

To compare the clinical outcomes of intraperitoneal bupivacaine instillation vs placebo as preemptive analgesia in patients undergoing open appendectomy

Eligibility criteria

Qualifiers

Patients presenting to the emergency department undergoing open appendectomy.

Disqualifiers

Patients undergoing interval appendectomy or having perforated appendix as evident by examination (abdominal tenderness/ fever) and USG findings (presence of abscess, fluid collection, or free air).

Uncontrolled medical disease (DM: BSL >200mg/dl, HTN: BP >140/90)

History of chronic kidney or liver disease/ psychiatric illness/ Active peptic ulcer disease (as determined on history and medical records)

Alcoholics

Trial design

Treatments tested in this trial

  • Bupivacain
  • Normal Saline

Treatment groups

60 Participants
are divided into 2 treatment groups

Sponsors and collaborators

Sardar Umer Rehman

Lead sponsor

Services Institute of Medical Sciences, Pakistan

Sponsor institution

Services Institute of Medical Sciences, Pakistan

Collaborator