About this trial
Through a triple-blinded randomized control trial, the primary purpose of this pilot study is to assess the efficacy of administering peri-operative contralateral corticosteroid injection in patients undergoing TKA. The secondary outcome was to assess the effect of contralateral corticosteroid injection on pain and functional outcomes of patients undergoing TKA.
Eligibility criteria
Qualifiers
Patients 18 years of age and older
Primary osteoarthritis diagnosis with indication for primary elective unilateral TKA
No previous contralateral knee injections (steroids/biologics) within one year of study
Not scheduled for bilateral TKA or a subsequent staged contralateral TKA within the next six months
Disqualifiers
Other aetiologies of OA that warrants TKA (inflammatory or post traumatic arthritis)
Cognitive impairment (dementia, Alzheimer's, uncontrolled delirium) which will prevent patients from completing primary outcome measure or comply with follow-up requirements
Previous TKA or ORIF or nailing on either knee
Previous or active knee infection or extensor mechanism disruption
Trial design
Treatments tested in this trial
- Corticosteroid Injection - 80mg methylprednisolone (total volume 2ml) with 6 mL of 1% Bupivacaine without epinephrine (Total Volume 8 mL).
- Band-Aid