Deep Brain Stimulation for Refractory Trigeminal Neuralgia with a Pontine Lesion
ConditionTrigeminal Neuralgia
Trial statusRecruiting
Trial phasePhase 1
Trial typeInterventional
Biological sexAll
Age18+
SponsorUniversité de Sherbrooke
About this trial
The aim of this study is to assess the feasibility of deep brain stimulation for refractory trigeminal neuralgia due to a pontine lesion, as is usually seen in the context of multiple sclerosis.
These patients usually have severe intractable facial pain and current medical and surgical options generally fail to achieve long lasting pain relief.
Hoping to improve pain control in this population, the investigators of this trial propose a novel technique consisting of implanting a deep brain stimulation lead within the pontine lesion to modulate the generation of pain signals.
Eligibility criteria
Qualifiers
Adults of at least 18 years old
Refractory trigeminal neuralgia : failure of at least 3 drugs and at least two lesioning surgical interventions (radiosurgery, percutaneous rhizotomy, or open rhizotomy).
Pontine lesion proved by MRI in contact with trigeminal nerve tract
Disqualifiers
Absolute contraindication to MRI
Medical contraindication to the procedure
Trial design
Treatments tested in this trial
- Deep brain stimulation
Treatment groups
6 Participants
are divided into 1 treatment groupSponsors and collaborators
Source ClinicalTrials.gov