Effect of Liberal and Restrictive IV Fluids on Recovery After Gallbladder Surgery

Trial statusRecruiting
Trial phasePhase 1
Trial typeInterventional
Biological sexAll
Age18-60
SponsorKing Edward Medical University

About this trial

The goal of this clinical trial is to learn whether giving less intravenous (IV) fluid (restrictive administration) after surgery is as effective as giving more IV fluid (liberal administration) in maintaining body stability (homeostasis) among adults undergoing laparoscopic gallbladder removal (cholecystectomy).

The main questions it aims to answer are:

Does restrictive IV fluid administration maintain stable blood pressure, heart rate, and urine output after laparoscopic cholecystectomy?

Are there any differences in postoperative recovery or complications between restrictive and liberal fluid regimens?

Researchers will compare patients receiving liberal IV fluid administration with those receiving restrictive IV fluid administration to see if both methods maintain similar postoperative homeostasis and recovery outcomes.

Participants will:

Be adults aged 18-60 years (ASA class I-II) undergoing elective laparoscopic cholecystectomy.

Be randomly assigned to one of two groups:

Group A: Liberal IV fluid administration for 6 hours after surgery.

Group B: Restrictive IV fluid administration for 6 hours after surgery.

Have their vital signs (pulse, blood pressure, mean arterial pressure) and urine output recorded at multiple time points after surgery (immediate, 3, 6, 12, and 24 hours).

Eligibility criteria

Qualifiers

All patients undergoing elective cholecystectomy

Age : 18-60 years

All genders

ASA class 1 and 2

Disqualifiers

History of previous laparotomy

Perforated gall bladder

Duration of surgery more than 3 hours

More than 100ml intra operative blood loss

Trial design

Treatments tested in this trial

  • Lactated Ringer 500ml
  • Lactated Ringer 1000ml

Treatment groups

380 Participants
are divided into 2 treatment groups

Sponsors and collaborators