Effects of Peripheral Magnetic Stimulation on Cortical Excitability in Healthy Individuals

Trial statusRecruiting
Trial phasePhase 1
Trial typeInterventional
Biological sexAll
Age18-40
SponsorUniversidade Federal de Pernambuco

About this trial

This study investigates the immediate effects of different parameters (frequency, intensity, and pulse number) of peripheral magnetic stimulation (rPMS) on cortical excitability in healthy individuals. Using a randomized, double-blind crossover design, the research aims to identify optimal stimulation protocols for modulating neural activity. Outcomes include measurements of motor-evoked potentials (MEPs), intracortical inhibition (ICI), and facilitation (ICF). Findings may enhance non-invasive therapeutic strategies for neurological disorders.

Eligibility criteria

Qualifiers

None

Disqualifiers

None

Trial design

Treatments tested in this trial

  • Peripheral magnetic stimulation (90% of RMT + 1 Hz)
  • Peripheral magnetic stimulation (90% of RMT + 10 Hz)
  • Peripheral magnetic stimulation (90% of RMT + 25 Hz)
  • Peripheral magnetic stimulation (100% of RMT + 1 Hz)
  • Peripheral magnetic stimulation (100% of RMT + 10 Hz)
  • Peripheral magnetic stimulation (100% of RMT + 25 Hz)
  • Peripheral magnetic stimulation (110% of RMT + 1Hz)
  • Peripheral magnetic stimulation (110% of RMT + 10Hz)
  • Peripheral magnetic stimulation (110% of RMT + 25Hz)

Treatment groups

18 Participants
are divided into 9 treatment groups

9

Treatment groups

See each treatment group below.