Effetivity of Dutasteride and Aloe Vera Extract Combination on Angiogenesis and Obstruction on Benign Prostatic Hyperplasia

Trial statusRecruiting
Trial phasePhase 1
Trial typeInterventional
Biological sexMale
Age50+
SponsorUniversitas Diponegoro

About this trial

This study is a double blinded RCT with pre-post test design on the effect of combination of dutasteride and aloe vera, compared to dutasteride only, on uroflowmetry results, prostate volume, and VEGF serum level among patients with benign prostate hyperplasia. The treatment was given for 12 weeks

Eligibility criteria

Qualifiers

Diagnosed with BPH clinically or radiologically (prostate volume > 30 gram, Qmax <15 mL/s)

Willing to participate to the study

Disqualifiers

Clinically or radiologically suspected of having prostatic cancer

Previous prostatic surgery

Patients with urinary retention

Patients with BPH complications: urinary tract infections, urolithiasis, or hydroneprhosis

Trial design

Treatments tested in this trial

  • Aloevera + dutasteride
  • Dutasteride (0.5mg)

Treatment groups

84 Participants
are divided into 2 treatment groups

Sponsors and collaborators