Efficacy of ICG-based NIR Imaging in Intralesional Curettage of Giant Cell Tumors of Bone in Limbs: a Prospective, Single-center, Single-arm, Open Study

ConditionGiant Cell Tumor of Bone

Trial statusRecruiting

Trial phasePhase 1, Phase 2

Trial typeInterventional

Biological sexAll

Age18-65

SponsorTang Xiaodong

About this trial

ICG fluorescence imaging will be applied during the intralesional curettage of giant cell tumor of bone in the limbs. This study aims to preliminarily explore whether ICG fluorescent-guided curettage could find small residual tumors and reduce the recurrence rate of tumor.

Eligibility criteria

Qualifiers

. Aged 18-65.

Biopsy confirmed giant cell tumor of bone.

The lesions located in the limbs.

This operation is the initial treatment.

Disqualifiers

. Known allergy to iodine contrast, indocyanine green or bone cement.

. Severe hepatic and renal insufficiency.

. During pregnancy or lactation.

. Have other malignant tumors and are receiving related medical treatment.

Trial design

Treatments tested in this trial

ICG (Indocyanine Green)

Treatment groups

45 Participants

are divided into 1 treatment group

Sponsors and collaborators

Tang Xiaodong

Lead sponsor

Peking University People's Hospital

Sponsor institution

Source ClinicalTrials.gov