Evaluating Safety, Tolerability, and Efficacy of Autologous MitoCell Transplantation in Subjects With Idiopathic Parkinson's Disease

Trial statusNot yet recruiting
Trial phasePhase 1
Trial typeInterventional
Biological sexAll
Age45-70
SponsorTaiwan Mitochondrion Applied Technology Co., Ltd.

About this trial

Primary Objective: To assess the safety profile of autologous MitoCell administered to subjects with idiopathic Parkinson's disease (PD)

Secondary Objective: To explore the efficacy and safety of MitoCell given as the recommended dose by stereotactic intrastriatal implantation

Eligibility criteria

Qualifiers

Provision of signed and dated informed consent form

Aged 45 to 70 years old (inclusive) at Screening

Idiopathic Parkinson's disease patients who meet the diagnostic criteria of the "Movement Disorder Society Clinical Diagnostic Criteria for Parkinson's disease"

With at least 5 years since the diagnosis of Parkinson's disease

Disqualifiers

Atypical or secondary Parkinsonism

With neurodegenerative disorders other than PD

Unable to receive MRI or PET scanning

With any concomitant disorder that would contraindicate coagulation, general anesthesia, or stereotactic neurosurgery

Trial design

Treatments tested in this trial

  • Aadipose-Derived Mesenchymal Stem Cells

Treatment groups

9 Participants
are divided into 1 treatment group

Locations

This trial has no locations