Evaluation of PET 18F-Fludarabine for the Initial Assessment and End-treatment of Symptomatic Multiple Myeloma Patients

ConditionMyeloma
Trial statusRecruiting
Trial phasePhase 1
Trial typeInterventional
Biological sexAll
Age18+
SponsorNantes University Hospital

About this trial

The objective of this exploratory study is to evaluate, for the first time, the sensitivity of 18F-Fludarabine to the initial diagnosis of MM compared to FDG-PET and MRI. The interest of this molecule will also be investigated as part of the end-of-treatment therapeutic evaluation.

Eligibility criteria

Qualifiers

Symptomatic MM in the first line in patients who are not candidates for autologous bone marrow transplantation.

Patients eligible for one of the treatments considered as standard in a patient who is not eligible for autograft, according to ESMO's European recommendations

MM with measurable disease either by the serum evaluation of the monoclonal component or by the determination of free light chains (serum or urinary).

Patient affiliated with a social insurance scheme

Disqualifiers

Age under 18 years

Pregnancy or breastfeeding

Male or female refusing birth control conditions

Primary AL amyloidosis and myeloma complicated by amyloidosis

Trial design

Treatments tested in this trial

  • 18F-Fludarabine

Treatment groups

35 Participants
are divided into 1 treatment group

Sponsors and collaborators