Evaluation of the Effect of Itraconazole on the Pharmacokinetics of HS-20093 in Patients With Advanced Solid Tumors

Trial statusRecruiting
Trial phasePhase 1
Trial typeInterventional
Biological sexAll
Age18+
SponsorHansoh BioMedical R&D Company

About this trial

The primary objective of this study is to evaluate the effect of itraconazole on the pharmacokinetics of HS-20093 in patients with advanced solid tumors.

Eligibility criteria

Qualifiers

Histologically or cytologically confirmed advanced solid tumors that have failed standard therapy or are intolerant to standard treatment.

According to RECIST 1.1 criteria, participants must have at least one target lesion.

ECOG performance status score of 0-1 with no deterioration within 2 weeks prior to the first dose.

Minimum expected survival greater than 12 weeks.

Disqualifiers

Patients with a contraindication for receiving itraconazole according to the prescribing information

Patients with severe, uncontrolled, or active cardiovascular diseases

Trial design

Treatments tested in this trial

  • HS-20093
  • Itraconazole

Treatment groups

18 Participants
are divided into 1 treatment group

Sponsors and collaborators