F-Tryptophan PET/CT in Human Cancers

Trial statusRecruiting
Trial phasePhase 1
Trial typeInterventional
Biological sexAll
Age18+
SponsorBarbara Ann Karmanos Cancer Institute

About this trial

Imaging procedures such as 1-(2-\[18F\]FLUOROETHYL)-L-Tryptophan PET/CT in patients with cancers may help doctors assess a patient's response to treatment and help plan the best treatment in the future. The purpose is to see if there can be a better differentiation of tumor and non-tumor tissue where the tumor tissue has a higher uptake of Tryptophan.

Eligibility criteria

Qualifiers

Age ≥18 years.

Targeted lesion (tumor) is at least 1 cm in diameter as shown by clinical imaging.

Patient is able to lie in the PET/CT scanner for at least 70 minutes while undergoing scanning.

Women of childbearing potential must not be pregnant or breastfeeding.

Disqualifiers

Patients who are pregnant or lactating are excluded.

Severe increased intracranial pressure, status epilepticus, or other symptoms requiring emergency or urgent intervention.

Tumor surgery or radiation within 1 month prior to the PET scan

Tumor-directed therapy within 3 months to the area of planned imaging.

Trial design

Treatments tested in this trial

  • 1-(2-[18F]FLUOROETHYL)-L-Tryptophan

Treatment groups

24 Participants
are divided into 1 treatment group

Sponsors and collaborators

Barbara Ann Karmanos Cancer Institute

Lead sponsor

Washington University School of Medicine

Collaborator