This study aim to investigate the safety and exploratory efficacy of STUP-001 which is AAV-based spinal cord injury investigational product.
Male and female adults aged 19 to 60 years at the time of obtaining informed consent.
AIS-A: Complete loss of sensory and motor function.
AIS-B: Partial preservation of sensory function with complete motor paralysis
Patients who have been diagnosed with traumatic spinal cord injury for at least 6 months at the time of screening.
Patients diagnosed with traumatic spinal cord injury (SCI) classified as AIS-C or D at the time of screening.
Myocardial infarction or unstable angina within the past 6 months.
QTc interval ≥ 450 msec or clinically significant electrocardiographic (ECG) abnormalities.
Congestive heart failure (CHF) classified as New York Heart Association (NYHA) Class II or higher.
Yonsei University
Lead sponsor
Stand Up Therapeutics INC.
Collaborator