Food and Ethnicity Effects on Pharmacokinetics and Safety of JPI-547 in Healthy Male Participants

Trial statusNot yet recruiting
Trial phasePhase 1
Trial typeInterventional
Biological sexMale
Age19-50
SponsorOnconic Therapeutics Inc.

About this trial

This study aims to evaluate the effects of food or ethnicity on the pharmacokinetics and safety/tolerability of JPI-547 after a single oral administration in healthy male Korean, Caucasian, and Chinese participants.

Eligibility criteria

Qualifiers

Healthy Korean, Caucasian, or Chinese male participants aged 19 to 50 years at screening

Body weight between 50.0 and 90.0 kg and BMI between 18.5 and 29.9 kg/m²

Able to understand the study and provide written informed consent

Considered suitable for study participation by the investigator based on medical history, physical examination, and clinical laboratory tests

Disqualifiers

Clinically significant medical or surgical history

Gastrointestinal disease or surgery affecting drug absorption

Hypersensitivity to PARP inhibitors or other significant drug allergy

Drug abuse history or positive drug screening

Trial design

Treatments tested in this trial

  • JPI-547

Treatment groups

36 Participants
are divided into 2 treatment groups

Sponsors and collaborators