GIC-102, Intravenous Allogeneic NK Cells, in Subjects With Advanced Solid Cancers and R/R Hematologic Malignancies

Trial statusRecruiting
Trial phasePhase 1, Phase 2
Trial typeInterventional
Biological sexAll
Age19+
SponsorGI Cell, Inc.

About this trial

This is a first-in-human trial to investigate the safety, tolerability, pharmacokinetics, pharmacodynamics, and antitumor effects of GIC-102 in patients with advanced solid tumors, relapsed/refractory non-hodgkin lymphoma, and multiple myeloma.

Eligibility criteria

Qualifiers

At least 19 years of age

Advanced solid tumors, relapsed/refractory non-hodgkin lymphoma, and multiple myeloma

At least one measurable or evaluable lesion

Eastern Cooperative Oncology Group performance status 0 or 1

Disqualifiers

Clinically significant cardiovascular disease within 24 weeks

Primary malignant tumor other than the indications for this study

The following diseases

Severe infection or other uncontrolled active infectious disease requiring administration of systemic antibiotics or antivirals within 4 weeks

Trial design

Treatments tested in this trial

  • GIC-102
  • GIC-102

Treatment groups

50 Participants
are divided into 2 treatment groups

Sponsors and collaborators