Golcadomide, Poseltinib, and Rituximab for Relapsed/Refractory Diffuse Large B-cell Lymphoma

Trial statusNot yet recruiting
Trial phasePhase 1, Phase 2
Trial typeInterventional
Biological sexAll
Age19+
SponsorSeoul National University Hospital

About this trial

This trial is a proof-of-concept, pilot study, phase I/II clinical trial aimed at generating preliminary data on the combination of golcadomide, poseltinib, and rituximab.

Eligibility criteria

Qualifiers

Subjects must satisfy the following criteria to be enrolled in the study

Subject is ≥ 19 years of age at the time of signing the informed consent form (CRF).

Subject must understand and voluntarily sign an ICF prior to any study-related assessments/procedures being conducted.

Subject is willing and able to adhere to the study visit schedule and other protocol requirements.

Disqualifiers

Subject who has had prior treatment with golcadomide.

Subject who has had prior treatment with BTK inhibitor.

Subject has life expectancy ≤ 2 months.

Subject has previously received solid organ transplantation.

Trial design

Treatments tested in this trial

  • Golcadomide + Poseltinib + Rituximab

Treatment groups

20 Participants
are divided into 1 treatment group