High Potency Cannabis: Acute and Protracted Effects
Trial statusRecruiting
Trial phasePhase 1
Trial typeInterventional
Biological sexAll
Age21-55
SponsorUniversity of California, Los Angeles
About this trial
The purpose of this research is to assess the effects of smoked cananbis when cannabis is smoked during periods of cannabis use as usual and after a brief period of abstinence.
Eligibility criteria
Qualifiers
• Male or non-pregnant and non-lactating females aged 21-55 years
Report cannabis smoking near daily
Not currently seeking treatment for their cannabis use
Have a Body Mass Index from 18.5 - 34kg/m2.
Disqualifiers
Meeting DSM-V criteria for any substance use disorder other than cannabis, nicotine, caffeine
Do not have positive urine toxicology for cannabis use during screening
Evidence of severe psychiatric illness (e.g. mood or anxiety disorder with functional impairment or suicide risk, schizophrenia) judged by the study physician (and PI) to put the participant at greater risk of experiencing adverse events due to completion of study procedures, interfere with their ability to participate in the study, or their capacity to provide informed consent.
Report using other illicit drugs in the prior 4 weeks
Trial design
Treatments tested in this trial
- Placebo Comparator: Placebo
- Low dose THC
- High dose THC
Treatment groups
30 Participants
are divided into 3 treatment groupsSponsors and collaborators
University of California, Los Angeles
Lead sponsor
California Department of Cannabis Control (DCC)
Collaborator
Source ClinicalTrials.gov