Hyperpolarized Imaging in Diagnosing Participants With Glioma

Participants must be > 18 years old and with a life expectancy > 12 weeks.

Participants must have a Karnofsky performance status of ≥ 60.

Participants must have adequate renal function (creatinine < 1.5 mg/dL) before starting therapy. This tests must be performed within 60 days prior to Hyperpolarized Imaging scan.

Participants must not have any significant medical illnesses that in the investigator's opinion cannot be adequately controlled with appropriate therapy, would compromise the patient's ability to tolerate the imaging examination or any disease that will obscure toxicity or dangerously alter response to the imaging agent.