Impact of Cannabis Consumption on Psychotic Symptoms and Reality Monitoring in Patients With Schizophrenia: a Real-life Study

ConditionSchizophrenia
Trial statusNot yet recruiting
Trial phasePhase 1, Phase 2
Trial typeInterventional
Biological sexAll
Age18-65
SponsorCentre Hospitalier Charles Perrens, Bordeaux

About this trial

This study aims to examine the dual effects of cannabis consumption on both positive and negative symptoms of schizophrenia, across laboratory and real-world contexts. By integrating ecological momentary assessment (EMA) with cognitive tasks such as reality monitoring, the research seeks to clarify how cannabis use influences symptom severity and cognitive functioning in individuals with schizophrenia. Gaining insight into these relationships may contribute to the development of more effective management strategies and ultimately improve outcomes for patients living with schizophrenia.

Eligibility criteria

Qualifiers

Clinically stable and in the residual (non-acute) phase of illness,

No change in antipsychotic treatment for at least 1 month,

Outpatient, ambulatory care,

No uncontrolled positive symptoms (assessed using PANSS)

Disqualifiers

Psychiatric comorbidities: autism, bipolar disorder.

Current criteria for any other substance use disorder except for nicotine use disorder.

Any medical condition hindering the study and/or use of the smartphone application.

Patients with somatic, cognitive or other disorders preventing the use of the device (deafness, impaired vision, illiteracy….).

Trial design

Treatments tested in this trial

  • Ecological Momentary Assessment (EMA) and Reality Monitoring tasks

Treatment groups

120 Participants
are divided into 2 treatment groups

Locations

This trial has no locations