About this trial
The goal of our study is to explore how treatments affect the bone immune microenvironment and determine the best treatment options for patients with metastatic kidney cancer to the bone. This could prevent skeletal complications and improve patient outcomes.
Eligibility criteria
Qualifiers
None
Disqualifiers
Signed Written Informed Consent
Ability to understand and the willingness to sign a written informed consent document.
Participants must have signed and dated an IRB/IEC approved written informed consent form in accordance with regulatory and institutional guidelines. This must be obtained before the performance of any protocol related procedures that are not part of normal participant care.
Participants must be willing and able to comply with scheduled visits, treatment schedule, laboratory testing, and serial biopsy schedule.
Trial design
Treatments tested in this trial
- Cabozantinib
- Nivolumab
Treatment groups
Locations
Sponsors and collaborators
M.D. Anderson Cancer Center
Lead sponsor
Exelixis
Collaborator