NIFR Image-guided Surgery for Malignant Soft Tissue Tumor With Low-dose SWIG Technique

ConditionsDermatofibrosarcoma Protuberans (DFSP)Skin Squamous Cell Carcinoma

Trial statusNot yet recruiting

Trial phasePhase 1

Trial typeInterventional

Biological sexAll

AgeNot listed

SponsorThe Plastic Surgery Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College

About this trial

This research study will evaluate how near-infrared fluorescence (NIRF) imaging with low-dose second window indocyanine green (ICG) can assist in the radical resection and pathologic diagnosis of malignant soft tissue sarcoma, such as dermatofibrosarcoma protuberans (DFSP) and skin squamous cell carcinoma (sSCC) during surgery.

Eligibility criteria

Qualifiers

Patients with DFSPs or sSCC in heads, extremities or trunk

Disqualifiers

seafood/iodine allergy

hyperthyroidism

pregnancy

myasthenia gravis

Trial design

Treatments tested in this trial

ICG administration
ICG administration
ICG administration
ICG administration

Treatment groups

592 Participants

are divided into 6 treatment groups

Treatment groups

See each treatment group below.

Locations

This trial has no locations

Sponsors and collaborators

The Plastic Surgery Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College

Lead sponsor

Peking University Third Hospital

Collaborator

Chinese PLA General Hospital

Collaborator

Peking University International Hospital

Collaborator

Source ClinicalTrials.gov