Optimal Anesthetic for Corticosteroid Injections for Knee Osteoarthritis

Trial statusRecruiting
Trial phasePhase 1
Trial typeInterventional
Biological sexAll
Age18+
SponsorFoundation for Orthopaedic Research and Education

About this trial

To evaluate pain relief from corticosteroid injection with and without anesthetic as well as with variable volume of anesthetic. Pain relief will be measured using the VAS pain score at the time of the injection as well as several time points following the injection to capture pain relief longevity. The investigators intend to evaluate how well the patients tolerate corticosteroid mixtures without anesthetic as well as with different volumes of anesthetic. Primary measure will be the time from procedure when postoperative status is considered success (as measured by global perceived improvement score).

Eligibility criteria

Qualifiers

Patients must be 18 years of age and be able to consent for themselves.

OA grade Kellgren Lawrence Stage II or III.

Diagnosis of primary osteoarthritis.

Disqualifiers

Patients with other forms of arthritis such as inflammatory arthritis.

History of narcotic use for the past 6 months.

Kellgren Lawrence arthritis grade 1 or 4.

Pregnant women and prisoners.

Trial design

Treatments tested in this trial

  • Kenalog with bupivacaine Injection

Treatment groups

75 Participants
are divided into 3 treatment groups

Sponsors and collaborators

Foundation for Orthopaedic Research and Education

Lead sponsor

Florida Orthopaedic Institute

Collaborator