About this trial
This study evaluated the safety and efficacy of SHR-8068 in combination with Adebrelimab and other anti-tumor drugs in the treatment of advanced renal cell carcinoma
Eligibility criteria
Qualifiers
Age 18 to 75 years old (including boundary values)
Volunteer to participate in this clinical study and sign informed consent;
ECOG score 0-1;
Expected survival ≥3 months;
Disqualifiers
Have previously used or are currently using HIF inhibitors.
Had received chemotherapy, immunotherapy, targeted therapy, anti-tumor traditional Chinese medicine or other clinical research drugs within 4 weeks prior to the first administration of the study; Palliative radiotherapy was received within 2 weeks before the first administration.
Live attenuated vaccines are used within a certain period of time before the first medication as stipulated in the plan, or it is expected that such vaccines will be needed during the treatment period.
Undergoing major surgical treatment within a certain period of time after the first administration of medication (excluding diagnosis) or expecting major surgical treatment during the study period.
Trial design
Treatments tested in this trial
- SHR-8068;Adebrelimab ;Bevacizumab
- SHR-8068;Adebrelimab ;HS-10516
- SHR-8068; Adebrelimab ; Bevacizumab ;HRS-10516