"Selinexor+Pegaspargase+Dexamethasone"in Ⅰ/Ⅱ NKTCL

ConditionsNKTCLSelinexor
Trial statusRecruiting
Trial phasePhase 1, Phase 2
Trial typeInterventional
Biological sexAll
Age18-70
SponsorMingzhi Zhang

About this trial

evaluate the efficacy and safety of "Selinexor+pegaspargase+dexamethasone" in early stage NK/ T-cell lymphoma

Eligibility criteria

Qualifiers

Age 18-70 years old, ECOG score 0-2; (including those aged 18 and 70);

Pre-survival time > 6 months;

The pathological tissue was confirmed as NK/T cell lymphoma (the pathological report of the first three months of enrollment could be accepted) (Note: If there is any doubt about the pathological diagnosis, domestic third-party consultation could be organized);

Clinical stage Ⅰ to Ⅱ (CA stage) with at least one measurable lesion;

Disqualifiers

Refuse to collect blood samples;

Previous allergy to any of the drugs in the program;

Pregnant and lactating women;

Major diseases that the investigator believes can cause interference with the test;

Trial design

Treatments tested in this trial

  • Selinexor+pegaspargase+dexamethasone

Treatment groups

50 Participants
are divided into 1 treatment group

Sponsors and collaborators

Mingzhi Zhang

Lead sponsor

Zhengzhou University

Sponsor institution