Study of S-892216 Long-acting Injectable (LAI) in Healthy Adult Participants

Trial statusRecruiting
Trial phasePhase 1
Trial typeInterventional
Biological sexMale
Age18-55
SponsorShionogi

About this trial

The purpose of this study is to investigate the safety, tolerability, and pharmacokinetics (PK) of single- and multiple-dose administration of S-892216-LAI in healthy adults.

Eligibility criteria

Qualifiers

Body mass index (BMI) ≥18.5 and ≤32.0 kilograms (kg)/square meter (m²)

Disqualifiers

Presence or history of cardiovascular, respiratory, hepatic, renal, gastrointestinal, endocrinological, hematological, neurological, or ophthalmological (for example, increased intra-ocular pressure) disorders capable of significantly altering the absorption, metabolism, or elimination of drugs; constituting a risk when taking the study intervention; or interfering with the interpretation of data per the investigator's assessment.

History of cancer except for basal cell or squamous epithelial carcinomas of the skin that have been resected with no evidence of metastatic disease for 3 years.

Require medication or other treatment (for example, dietary restrictions or physical therapy).

Participated in any other clinical study involving an investigational study intervention or any other type of medical research within 30 days, or 5 times the half-life of the investigational drug, before signing of the informed consent form (ICF) for this study or who are currently participating in such a study.

Trial design

Treatments tested in this trial

  • S-892216-LAI
  • Placebo

Treatment groups

98 Participants
are divided into 2 treatment groups

Sponsors and collaborators