Study of ZG005 in Combination With Gecacitinib in Participants With Advanced Cervical Cancer

Trial statusRecruiting
Trial phasePhase 1, Phase 2
Trial typeInterventional
Biological sexFemale
Age18-75
SponsorSuzhou Zelgen Biopharmaceuticals Co.,Ltd

About this trial

This is a multicenter, open-label phase I/II study in patients with advanced cervical cancer designed to evaluate the safety, tolerability, and preliminary efficacy of ZG005 in combination with Gecacitinib ± bevacizumab.

Eligibility criteria

Qualifiers

Fully understand the study and voluntarily sign the informed consent form.

Female 18-75 years of age;

Eastern Cooperative Oncology Group (ECOG) Performance Status of 0 or 1.

Histologically or cytologically confirmed advanced cervical cancer, including squamous cell carcinoma, adenocarcinoma, or adenosquamous carcinoma.

Disqualifiers

Patients were deemed unsuitable for participating in the study by the investigator for any reasons.

Trial design

Treatments tested in this trial

  • ZG005
  • Gecacitinib
  • Bevacizumab

Treatment groups

120 Participants
are divided into 2 treatment groups