Study of ZG005 in Combination With Gecacitinib in Patients With Relapsed or Refractory Lymphoma

ConditionLymphoma
Trial statusRecruiting
Trial phasePhase 1, Phase 2
Trial typeInterventional
Biological sexAll
Age18+
SponsorSuzhou Zelgen Biopharmaceuticals Co.,Ltd

About this trial

PART 1:

1. To explore the safety of ZG005 in combination with Gecacitinib in patients with relapsed or refractory lymphoma. 2. To determine the recommended Phase II dosing regimen for relapsed or refractory lymphoma.

PART 2:

To evaluate the efficacy of ZG005 in combination with Gecacitinib in patients with relapsed or refractory lymphoma.

Eligibility criteria

Qualifiers

Fully understand this study and voluntarily sign the ICF;

Age ≥18 at ICF signing, regardless of gender;

Histologically confirmed relapsed or refractory lymphoma.

Disqualifiers

Lymphoma with known CNS involvement;

Severe cardiovascular/cerebrovascular diseases.

Any other reason deeming the participant unsuitable for the study, as judged by the investigator.

Trial design

Treatments tested in this trial

  • ZG005 for Injection
  • Gecacitinib Hydrochloride Tablets

Treatment groups

60 Participants
are divided into 2 treatment groups