Study of ZGGS18 in Combination With ZG005 in Patients With Advanced Solid Tumors

Trial statusRecruiting
Trial phasePhase 1, Phase 2
Trial typeInterventional
Biological sexAll
Age18-75
SponsorSuzhou Zelgen Biopharmaceuticals Co.,Ltd

About this trial

This trial is designed to assess the tolerability, safety, pharmacokinetic profile, and preliminary efficacy of the combination of ZGGS18 and ZG005 in patients with advanced solid tumors, including advanced cervical cancer, hepatocellular carcinoma, neuroendocrine cancer, and lung cancer.

Eligibility criteria

Qualifiers

Fully understand this study and voluntarily sign the ICF.

Age 18-75 years, no gender restriction.

Patients with advanced solid tumors who have failed standard treatment or are intolerant to standard treatment, as confirmed by histopathology or cytology.

Disqualifiers

Medical history, CT scan, or MRI indicates the presence of CNS metastases.

Other malignancies within 5 years.

Any other reason deeming the participant unsuitable for the study, as judged by the investigator.

Trial design

Treatments tested in this trial

  • ZGGS18 for Injection
  • ZG005 for Injection

Treatment groups

60 Participants
are divided into 2 treatment groups